Taking rutile titanium dioxide as raw material and the amount of dispersant, the coating agent ratio of zirconium and aluminum, the stirring velocity and ageing time as influencing factors, the L9(34) orthogonal experiment is conducted to study the optimum technical conditions for zirconium and aluminum dualistic coating on the rutile titanium dioxide. The optimum conditions is determined through Zeta potential analyzing, and the structure and performance of the obtained base material A and the coated sample B are characterized by scanning electron microscope(SEM), transmission electron microscope (TEM), fourier transform infrared spectrometer (FT-IR) and X-ray powder diffractometer(XRD) etc. Experimental results demonstrate that the stable ZrO2 and Al2O3 coating is formed through Zr—O—Ti and Zr—O—Al bonding on the surface of the rutile titanium dioxide under the conditions that the dispersant mass fraction is 1.0%, the zirconium and aluminum mass ratio is 2:1, the stirring velocity is 270 r/min and the ageing time is 2 hours, respectively.