To solve the problems of the honeycomb paperboard in poor initial cushioning properties, slow drying and being easily mildewed, a new processing technology has been introduced to deal with the honeycomb core with slotting process, with the purpose to improve its cushioning performance as far as possible while not to reduce the compressive strength distinctively. The static compression of honeycomb paperboard (about 30 mm) was tested with the method of orthogonal test in order to investigate the influences of the process parameters (width, depth and distance of the slot) on the performance of the honeycomb paperboard. The results show that the honeycomb paperboard has the better over-all properties of compression resistance and cushioning when the adoptive parameters are respectively with the slot width of 2.5 mm, the slot depth of 3 mm and the slot distance of 32 mm.